Dodecyldimethylsulfopropylbetaine (DDSB) CAS 14933-08-5

>> Product Introduce

Dodecyldimethylsulfopropylbetaine (DDSB)

CAS 14933-08-5

Dodecyldimethylsulfopropylbetaine (CAS 14933-08-5) is a high-purity zwitterionic surfactant characterized by its exceptional stability across a broad pH range from strong acids to strong alkalis. This sulfobetaine derivative features both a quaternary ammonium cation and a sulfonate anion within the same molecule, giving it a net neutral charge that makes it particularly useful for non-denaturing protein solubilization and purification. It is widely employed in biochemical research for membrane protein extraction, protein crystallization, and as a dynamic coating agent in capillary electrophoresis to suppress electroosmotic flow and prevent protein adsorption.

>> Main Uses

Dodecyldimethylsulfopropylbetaine (DDSB, CAS 14933-08-5) is a zwitterionic sulfobetaine surfactant widely used for the non-denaturing solubilization, purification, and crystallization of membrane proteins in biochemical and structural biology research, including NMR and electron microscopy studies. It also serves as an effective dynamic capillary coating agent in capillary electrophoresis to suppress electroosmotic flow and prevent adsorption of cationic proteins, achieving high protein recovery rates and exceptional separation efficiency. Beyond research applications, DDSB functions as a mild, pH-stable surfactant in personal care products such as shampoos and body washes, as well as in industrial formulations including cleaning agents, textile antistats, oilfield thickeners, and contact lens solutions.

>> Technical Specifications

>> Package and Storage Conditions

• Packaged in lBC tanks or blue plastic drums.

• Store in a sealed container in a cool, dry place.

• Keep away from fire sources and oxidants.

• Avoid high temperatures and humid environments to prevent caking due tomoisture absorption.